Yellow Fever Vaccination

What is it?

Attenuated 17D strain Yellow Fever (Live) Vaccine in a freeze dried form.

Manufacturing process?

Virus has been propagated in specific pathogen free chick embryos.

Who must not have it?

• People who have severe allergic reaction to egg or chicken.
• Children under 6 months of age.
• People who have reduced immunity due to disease or treatment.
• Symptomatic HIV positive people
• Pregnant or breast feeding women
• People with disease of thymus or have their thymus gland removed.
• People who are currently unwell with an infective process.

Other considerations:

• Yellow fever vaccine should not be administered within 4 weeks of another vaccine.
• Can be administered simultaneously with other live vaccines.

Common Side Effects:

• Headache - 18%
• Tiredness - 16.6%
• Injection site pain, swelling, bruise - 14%
• Fever 8.3%

Rare but Serious Adverse Reactions:

• Yellow Fever Vaccine Associated Neurotropic Disease (YEL-AND), a potentially life threatening condition of the nervous system
• Yellow Fever Vaccine Associated Viscerotropic Disease (YEL-AVD) previously known as Febrile Multiple Organ System Failure

What is it?

A potentially deadly illness presenting in a wide range from hardly any symptoms at all. Some people can fever, muscle pain back pain, headache, nausea and vomiting. This could last for 3-4 days. In a smaller number of people, they can go onto have severe fever, and failure of multiple organs leading to bleeding, jaundice and can lead to death in about 50% .

Treatment?

There are no specific treatments. Management is mainly supportive.

How to prevent?

Having Yellow Fever Vaccine, general mosquito bite prevention strategies.

Where is the disease present?

The disease is present in many South American countries as well as Sub-Saharan African countries. The latest list of Yellow Fever endemic countries can be found here.

What is it?

It is a micro-organism belonging to Arbovirus (arthropod/insect born) group of viruses belonging to a group called Favivirus. It is carried by day biting mosquitos. Monkeys and humans can remain as reservoirs for the mosquitos to transmit the infection.